Tramadol Hydrochloride Capsules 50mg

How to use Tramadol Hydrochloride Capsules 50mg

Tramadol is an opioid medication that is used to treat moderate to severe pain. It is sold in the market as Ultram. It has an immediate release formula. Usually, a patient starts feeling relief within one hour of taking the medicine. The medicine is available in longer-acting formulations also. Usually, it is also sold in combination with paracetamol by a pharmacist.

Strength and Benefits of Tramadol Capsules

The chemical composition of Tramadol is C16H25NO2 with a molecular mass of about 263.381 g·mol−1. The drug has a bioavailability of 70-75% by mouth, 100% if it is injected intramuscular and 77% if it is given by rectal route. The protein binding capacity of this drug is 20%. The onset of action is less than an hour.

The working mechanism of Tramadol Capsules

In the liver, Tramadol is converted to O-desmethyl Tramadol or desmetramadol. It is an opioid that has a stronger binding affinity to μ-opioid receptors. This is a serotonin-norepinephrine reuptake inhibitor which is also called SNRI.

The medicine was patented in 1963 under the name of “ Tramal”. By mid-1990’s it was approved in the United States of America as well as the United Kingdom. Now it is available as a generic medicine and is sold all around the world. It was the 35th most prescribed medicine in the United States of America in 2019. It had more than 19 million prescriptions that year alone.

Side Effects

Tramadol UK can be bought easily in the UK by any patient. However, just like the rest of opioids, Tramadol Capsules in the UK also have some side effects like:

  • Itchiness
  • Nausea
  • Constipation

Severe Side Effects

Sometimes, some patients may experience more severe side effects like:

  • Hallucinations
  • Seizures
  • Serotonin syndrome- which is the dysregulation of the neurotransmitter serotonin.
  • Drug addiction or substance abuse
  • Decreased body alertness


The dose or concentration varies upon the age of the patient as well as the underlying secondary conditions like liver or kidney problems. If the patient is experiencing severe pain, then the dose might be increased.

Where to buy Tramadol in the UK?

One needs to register first and then follow a legal process to Buy Tramadol in the UK. Sometimes companies can be different but they can sell their product names to one another. All this is done to boost sales and have another marketing strategy to Buy Sleeping Pills UK

Additional Information


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